In the last decade, major discoveries have been made in early diagnosis, prevention, and treatment, altering incidence, prognosis, and treatment responsivity. We have provided guidance about what works and what does not to inform decision-making, and highlighted areas for more research.Ĭerebral palsy is the most common physical disability of childhood.
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Effective medical and surgical interventions include anti-convulsants, bisphosphonates, botulinum toxin, botulinum toxin plus occupational therapy, botulinum toxin plus casting, diazepam, dentistry, hip surveillance, intrathecal baclofen, scoliosis correction, selective dorsal rhizotomy, and umbilical cord blood cell therapy. Effective allied health interventions include acceptance and commitment therapy, action observations, bimanual training, casting, constraint-induced movement therapy, environmental enrichment, fitness training, goal-directed training, hippotherapy, home programs, literacy interventions, mobility training, oral sensorimotor, oral sensorimotor plus electrical stimulation, pressure care, stepping stones triple P, strength training, task-specific training, treadmill training, partial body weight support treadmill training, and weight-bearing. Recent FindingsĮffective prevention strategies include antenatal corticosteroids, magnesium sulfate, caffeine, and neonatal hypothermia.
This article summarizes the best available evidence interventions for preventing and managing cerebral palsy in 2019. We conducted a systematic overview of best available evidence (2012–2019), appraising evidence using GRADE and the Evidence Alert Traffic Light System and then aggregated the new findings with our previous 2013 findings. Cerebral palsy is the most common physical disability of childhood, but the rate is falling, and severity is lessening.
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